Hey Doc,... we all have read, or heard, that the rifle is our best form of self defense and how a handgun is a good tool to get you to your rifle. I think in certain circumstances, a palm size handgun in a front pocket can possibly be more accessible than a primary concealed carry piece, and therefore could be quicker to defense,... as well as putting an attacker on the defense, and thereby allowing a few seconds to get a primary concealed defense piece.
Of course, if time allows, accessing your primary defense tool first, is more desirable.
Bottom line, a 22 palm size pocket piece is (IMO) better than throwing a punch,... before accessing a primary concealed defense piece, in a close up and personal attack.
There is a purpose for every self defense firearm made, when used within its limitations,... imo.