I have a 2004 F350 CC longbed SRW 6.0 that I bought 11 years ago with 48,000 miles on the clock. It now has 94,000. The only thing that I have had go wrong with it is the logic board on the FICM. I bought a new Dorman brand board from Amazon and replaced it myself. I also replaced the high pressure line on my power steering pump. Also, my degas bottle cracked where a hose goes to it. I bought a Dorman bottle at Autozone with a lifetime warranty and that cracked a year later, so they gave me a new one.
I run a custom tune loaded on with a SCT handheld tuner and will spank Mustangs, Camaro, and keep up with Corvettes. Not bad for a 21 foot, 8,000 lbs truck. The tune also tunes the trans which is extremely critical. I installed a MBRB turbo back exhaust on it with a muffler delete pipe and cat delete pipe, so it is straight piped from the turbo back and sounds awesome. So does the turbo at the tail pipe.
The inherent problems of the 6 liter are the TTY(torque to yield) head bolts which allow the heads to lift, blowing the head gaskets caused by a failed EGR cooler or oil cooler. Those failures are usually the result of casting sand left behind in the block. There is tons of information on Powerstroke.org
The 6.0 liter is a great motor and will be even greater if you take care of the known isssues such as putting ARP head studs, replacing the egr cooler with a Bulletproof egr cooler or a egr delete kit.
Don't be gun shy about buying a 6.0 liter. I wouldn't hesitate about taking my truck across country tonight. They are solid trucks. I wish I had a coil spring front end, but alas, it is leaf sprung.
I also have the ambulance package which comes with dual alternators. When my starter goes out, I will be replacing it with a 6.4 high torque gear reduced starter.
I would definitely stay away from the 6.4 Powerstroke and the new 6.7 Powerstroke up to 2015. Any 6.7 after 2015 is good to go. If you have any more questions, ask away.
One thing I would highly suggest is to run a OASIS report on the truck you plan on buying. Any dealer should pull it up for you or ask for someone on Powerstroke.org to run it for you. It is the vehicle service record for the trucks life
My truck has never hauled a 5th wheel trailer, but it does have the attachment points and electrical plug in in the bed for a over the cab camper.
It rides great, I run a Full Traction 4.5 inch lift, dual Bilstien shocks up front, single in the rears, dual Bilstien steering stabilizers, and BF Goodrich Velvet Ride shackles in the rear. My oldest son drove it door to door from his moms house in Prescott to my dads house in Vegas and back when he was 14 years old. Not by himself, I was in the passenger seat.
I get about 17 mpg on the freeway, and about 15 in the city.
ETA: I did have a right rear caliper stick causing the pad to wear down to the metal and causing me to buy a new rear rotor and some Hawks brake pads.